Addiction & Opioid Crisis Moonshot

Accelerate breakthroughs to end addiction and the opioid epidemic

A 9-Year Overnight Success Story: How Pelago Is Rebuilding Behavioral Health for the AI Era

Aug 21, 2026

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2 min read

A 9-Year Overnight Success Story: How Pelago Is Rebuilding Behavioral Health for the AI Era

Long-time StartUp Health member Dr. Yusuf Sherwani shares the decisions behind a 10x drop in treatment costs, raising $150M, and why he's rebuilding Pelago around AI-powered care

Access to Care Moonshot

Blog

Addiction & Opioid Crisis Moonshot

Health Moonshot Update

How Pelago cut addiction treatment costs by 10x – and why AI changes what's next

Aug 12, 2026

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2 min read

How Pelago cut addiction treatment costs by 10x – and why AI changes what's next

Pelago's Dr. Yusuf Sherwani on a decade of building addiction care, the metrics behind a $150M raise, and why Pelago is refounding itself for the age of AI.

Addiction & Opioid Crisis Moonshot

Video

Health Moonshot Update

Identifying addiction risk before the first prescription with Thrive Genetics

Jul 17, 2026

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1 min read

Identifying addiction risk before the first prescription with Thrive Genetics

Thrive Genetics CEO & Co-founder James Piacentino on the science behind Cares, a personalized tool helping providers flag addiction risk in oncology and orthopedics before pain medication is prescribed.

Addiction & Opioid Crisis Moonshot

Video

StartUp Health Event

From Flow State to FDA: How Sana Health Is Rewiring Pain and PTSD Care

Apr 15, 2026

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1 min read

From Flow State to FDA: How Sana Health Is Rewiring Pain and PTSD Care

StartUp Health community member Richard Hanbury of Sana Health shares how a personal breakthrough in pain led to the world’s first approved audiovisual neuromodulation device, and why building medical credibility is a step-by-step journey.

Access to Care Moonshot

Addiction & Opioid Crisis Moonshot

Video

Mental & Behavioral Health Moonshot

Sana Health Advances Toward Global Scale in Pain and PTSD Care

Feb 19, 2026

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3 min read

Sana Health Advances Toward Global Scale in Pain and PTSD Care

In this Health Moonshot Update, Unity Stoakes sits down with StartUp Health community member Richard Hanbury of Sana Health just prior to a major regulatory milestone: an FDA De Novo grant for neuropathic pain, creating a new class of audio-visual neuromodulation. Hanbury shares the decades-long journey behind Sana Health’s science, why neuropathic pain is the strategic wedge for broader mental health adoption, and how pivotal data showed a 78% reduction in gabapentinoid use in the active group. The conversation also explores Sana’s growing PTSD research with the US Department of Defense and Veterans Affairs, expanding studies in Israel, and why multimodal care is essential to the future of scalable pain and mental healthcare.

Access to Care Moonshot

Addiction & Opioid Crisis Moonshot

Video

Mental & Behavioral Health Moonshot

Addiction & Opioid Crisis Moonshot

A 9-Year Overnight Success Story: How Pelago Is Rebuilding Behavioral Health for the AI Era

How Pelago cut addiction treatment costs by 10x – and why AI changes what's next

Identifying addiction risk before the first prescription with Thrive Genetics

From Flow State to FDA: How Sana Health Is Rewiring Pain and PTSD Care

Sana Health Advances Toward Global Scale in Pain and PTSD Care

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