
The Digest for Health Transformers & Changemakers
Nine years ago, Dr. Yusuf Sherwani co-founded Pelago (then Quit Genius) as a virtual clinic for substance use disorder, long before telehealth was trusted, let alone expected. Since then, Pelago has cut the cost of treatment by 10x, raised $150M, and become a go-to partner for self-insured employers and health plans across all 50 states.
In this Health Moonshot Update, Sherwani talks about the failed pivots that came before Pelago found its model, why the company is "refounding" itself even after reaching scale, and Sona, its new AI mental health specialist built to triage and support care with a clinician always in the loop.
👉 Read, Watch, or Listen on Health Transformer Journal
🚀 Join the StartUp Health Community to Tell Your Story
Summer's winding down, and we're giving new members an extra reason to join now instead of later. StartUp Health membership is already built to keep you connected to the people, conversations, and opportunities driving the future of health – Fireside Chats, Expert AMAs, VIP event access, and a community of founders, funders, and operators who share your mission.
Join by September 1 and you'll also get your choice of a free audit: a website and brand audit, a pitch and story audit, or an AI ops audit. Sharpen your story or your systems, on us.
From foundation models for drug discovery to smart rings that diagnose sleep apnea in three nights, this week's raises span the globe – and the stage.
📈 Read the Weekly Roundup
With more than 2,400 videos, 11,000+ subscribers, and nearly a million views on YouTube, our video channel spotlights Health Transformers in action, showcasing how the right mindset, moonshot vision, and the spirit of an entrepreneur make anything possible. Recent videos feature conversations with leading experts like Lisa Suennen (AHA Ventures), Kimmi Grewal (Microsoft), and Holly Maloney (General Catalyst), alongside founders building the future of health.
🎥 Watch the Latest Videos
🚀 Boost Your Brand
From venture capital to executive insights to AI workshops and demos, we have exciting events happening inside the community in the months ahead. Join StartUp Health to catch the next live conversation and bring your own questions to the table.
🚀 Claim Your Seat
Toyin Ajayi, MD, CEO & Co-founder of Cityblock, on the company signing a definitive agreement to acquire Homeward Health in an all-stock transaction, alongside a $116 million Series E led by General Catalyst.
🔗 Read
Rafael López, CEO & Co-founder of Diagnostikare, on the company being awarded Mexico's ESR (Socially Responsible Company) distinction.
🔗 Read
Beth Sanders, CEO & Founder of LifeBio, on Apple Samsung tablets being shipped with LifeBio Memory app loaded.
🔗 Read
Silvia Zheng, COO & Co-founder of NeuDreamer, on the company’s team and collaborators publishing a new perspective in “Alzheimer’s & Dementia,” demonstrating that menopausal insomnia is a modifiable, sex-specific risk factor for Alzheimer’s disease.
🔗 Read
Today’s Sponsors
AI in financial services requires real trust and governance. Watch how Fin and Plaid are collaborating to give customers faster, more secure, and more personalized experiences, without giving up control. Watch now.
Creators lock in holiday calendars 90 days out. Structure commissions, recruit creators, and optimize your creator affiliate strategy before the rush with Levanta's 90-Day Holiday Sprint. Get the Free Guide.
Porkbun is the domain registrar people trust when they want low prices without the nonsense. Score most domains at cost, free perks like WHOIS privacy & SSL certificates, and real 24/7 human support. Save $1 On Your Domain
Help Us Spread the Word
When you shoot for the Moon, it’s important to surround yourself with people who help you get there.
Thank you for being part of StartUp Health’s global community leaning into health innovation. If you found this newsletter valuable, chances are others will too, so please feel free to pass it along.
And if you or your organization are interested in supporting this work through sponsorship or partnership, we’d love to hear from you. You can schedule a newsletter ad placement or check out our sponsorship opportunities. We also invite you to use our affiliate link to join us on Beehiiv, our new newsletter platform.


