StartUp Health community member Cala Health, the Burlingame, CA-based pioneer of wearable neuromodulation therapy for essential tremor and Parkinson's hand tremor, has secured $50M in growth financing from Trinity Capital to accelerate the commercial expansion of its FDA-cleared therapy. The new funding comes on the heels of FDA clearance earlier this month for the company's next-generation device, Cala kIQ Plus – a meaningful upgrade to the company's Transcutaneous Afferent Patterned Stimulation (TAPS) platform, which delivers personalized, non-invasive nerve stimulation through a wrist-worn device. Cala has also recently expanded patient access through Medicare coverage pathways, a critical step toward reaching the millions of Americans living with essential tremor and Parkinson's disease who have historically had few effective non-pharmacological options.

Under the leadership of CEO Deanna Harshbarger and President, Chief Innovation Officer & Founder Kate Rosenbluth, PhD, Cala has steadily built one of the most compelling commercial stories in wearable neuromodulation. Since joining the StartUp Health community, the company raised $50M in 2025, building on its 2022 $77M Series D round. With the latest tranche from Trinity Capital, kIQ Plus heading to market, and Medicare reimbursement opening the door to broader adoption, Cala is moving from clinical validation into full commercial scale.

Other reported global health innovation funding this week included:

Nervonik, a Los Angeles, CA-based clinical-stage medical device company developing next-gen peripheral nerve stimulation technologies for chronic pain, raised $52.5M led by Amzak Health, with participation from Elevage Medical Technologies, U.S. Venture Partners, Lumira Ventures, Foothill Ventures, and Shangbay Capital. <source>

Courier Health, a New York, NY-based technology company for managing patient experiences in life sciences, raised $50M led by Oak HC/FT, with participation from Norwest and Work-Bench. <source>

Minish Technology, a Los Angeles, CA-based medical device company, raised $22M led by VIG Partners. <source>

SquareMind, a Paris, France-based AI and robotics company developing solutions for dermatology, raised $18M in funding led by Sonder Capital, with participation from Deeptech 2030 Fund, Adamed Technology, Calm/Storm Ventures, and Teampact Ventures. <source>

Amperos Health, a New York, NY-based company that automates revenue cycle management using AI, raised $16M in Series A funding led by Bessemer Venture Partners, with participation from Uncork Capital and Neo. <source>

Bioxtreme, a Chicago, IL-based developer of neurorehabilitation technologies leveraging AI and its proprietary error augmentation approach to accelerate motor recovery, raised $15M led by Serra Holding. <source>

Zócalo Health, a Kenmore, WA-based tech-enabled, community-based primary care provider focused on serving Latino communities and other underserved populations, raised $15M led by EO Ventures, with participation from Talipot, Vamos Ventures, Animo Ventures, Acumen America, Sorenson Ventures, BarronKent, and Kapor Center. <source>

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Almanac Health, a San Francisco, CA-based clinical AI platform and evidence-based clinical decision support company, raised $10M led by F-Prime, with participation from General Catalyst and Lightspeed Venture Partners. <source>

LighthouseAI, a Los Angeles, CA-based company specializing in compliance solutions for the pharmaceutical supply chain, raised $8M led by Boxcars Ventures, with participation from TGVP and existing investors. <source>

Timeshifter, a New York, NY-based circadian technology company focused on travel, shift work and healthcare, raised $5.3M led by Skip Capital, with participation from individual and strategic investors. <source>

10x Science, a San Francisco, CA-based AI platform for drug discovery, raised $4.8M led by Initialized Capital, with participation from Y Combinator, Civilization Ventures, and Founder Factor. <source>

Magicare, a Bergenfield, NJ-based provider of an agentic operating system for post‑acute care, raised $3.6M from Mana Ventures. <source>

Calibre, a London, UK-based healthtech company advancing “Causal Health Navigation,” raised $3.3M led by Amino Collective, with participation from Daybreak Ventures, Cocoa Ventures, and a group of founders, operators and medical experts. <source>

Gravity Rail, a Houston, TX-based no-code AI operating system developer, raised $2.75M led by Redesign Health. <source>

Betterness, a Miami, FL-based provider of an augmented wellness platform, raised $2.5M in seed funding from individual investors. <source>

Waiv, a Paris, France-based AI technology company developing precision oncology tests, raised $2M from CRB Health Tech. <source>

TriFetch, a San Francisco, CA-based specialty clinic workflow automation platform, raised $1.9M led by Nexus Venture Partners, with participation from angel investors. <source>

Celerion, a Lincoln, NE-based clinical research company, raised an undisclosed amount from THL Partners. <source>

Nephronomics, a Dover, DE-based AI-bio precision medicine company, raised an undisclosed amount from CerraCap. <source>

Data is from StartUp Health Insights, the most comprehensive funding database for health innovation. Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox. Follow us on LinkedIn for daily updates on Health Moonshots.